Undetected cancer in clinical prostate biopsies
SND-ID: 2024-144. Version: 1. DOI: https://doi.org/10.57804/epa0-8v59
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Tillhörande dokumentation
Citering
Skapare/primärforskare
Eduard Chelebian
- Uppsala universitet, Institutionen för informationsteknologi
Carolina Wählby
- Uppsala universitet, Institutionen för informationsteknologi
Anders Bergh
- Umeå universitet, Institutionen för medicinsk biovetenskap
Forskningshuvudman
Beskrivning
Datasetet består av digitiserade godartade prostata H&E-biopsier från män med förhöjda PSA-värden. För mer information, se beskrivning på engelska:
This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up.
The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis. Conversely, 88 case patients with 254 biopsies were diagnos
This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up.
The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis. Conversely, 88 case patients with 254 biopsies were diagnosed with PCa of various ISUP grades within the 30 months following the initial diagnosis. Each case patient is accompanied by one to three control patients, paired for similar age, PSA value and year of diagnosis.
Patients were anonymized by assigning random case IDs and MRXS image files were anonymized by using the module in https://github.com/bgilbert/anonymize-slide. Visa mindre..
Data innefattar personuppgifter
Nej
Språk
Analysenhet
Population
Anonymised men from northern Sweden with raised serum prostate-specific antigen (PSA), an initial benign diagnosis in prostate needle biopsies and with subsequent separation in diagnostic trajectories.
Studiedesign
Kohortstudie: Retrospektiv
Tidsperiod(er) som undersökts
1997 – 2016
Antal individer/objekt
213
Dataformat / datastruktur
Övriga forskningshuvudmän
Medverkande
Christophe Avenel
- Uppsala universitet, Institutionen för informationsteknologi
Pernilla Andersson - Umeå universitet, Institutionen för medicinsk biovetenskap
Helena Järemo
- Umeå universitet, Institutionen för medicinsk biovetenskap
Etikprövning
Umeå - dnr Regionala Etikprövningsnämnden, 2010/366-31M
Forskningsområde
Vetenskap och teknologi (CESSDA Topic Classification)
Informationsteknik (CESSDA Topic Classification)
Datorseende och robotik (autonoma system) (Standard för svensk indelning av forskningsämnen 2011)
Medicinsk bildbehandling (Standard för svensk indelning av forskningsämnen 2011)
Medicin och hälsovetenskap (Standard för svensk indelning av forskningsämnen 2011)
Cancer och onkologi (Standard för svensk indelning av forskningsämnen 2011)
Urologi och njurmedicin (Standard för svensk indelning av forskningsämnen 2011)
