EpiHealth

SND-ID: ext0087-1.

Is part of collection at SND: Swedish Cohort Consortium (Cohorts.se), Scania Metadatabase for Epidemiology (SME)

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Contact

Associated documentation

Creator/Principal investigator(s)

Sölve Elmståhl - Lund University, Department of Clinical Sciences Medicine in Malmö. Division of Geriatric Medicine

Lars Lind - Uppsala University, Department of Medical Sciences

Maria Albin - Lunds University, Department of Laboratory Medicine, Lund, Division of Occupational and Environmental Medicine

Marju Orho-Melander - Lund University, Department of Clinical Sciences, Malmö, Division of Diabetes and cardiovascular disease - genetic epidemiology

Anders Bjartell - Lund University, Department of Clinical Sciences, Malmo, Division of Urological Cancers

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Sölve Elmståhl - Lund University, Department of Clinical Sciences Medicine in Malmö. Division of Geriatric Medicine

Lars Lind - Uppsala University, Department of Medical Sciences

Maria Albin - Lunds University, Department of Laboratory Medicine, Lund, Division of Occupational and Environmental Medicine

Marju Orho-Melander - Lund University, Department of Clinical Sciences, Malmö, Division of Diabetes and cardiovascular disease - genetic epidemiology

Anders Bjartell - Lund University, Department of Clinical Sciences, Malmo, Division of Urological Cancers

Ingemar Petersson - Lund University, Department of Clinical Science, Lund, Department of Orthopaedics

Paul Franks - Lund University, Department of Clinical Sciences, Malmo, Division of Genetic and Molecular Epidemiology

Karin Källén - Lund University, Department of Clinical Sciences, Lund, Tornblad Institute

Peter M Nilsson - Lund University, Faculty of Medicine

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Research principal

Lund University rorId

Description

The study consists of three parts:
1) Collection of data on lifestyle factors by a self-administered web-based questionnaire
2) Visit to a test center for collection of blood samples and recording of physiological parameters
3) The population is followed in registers for occurence of predefined emdpoints.
Repeated collection of data by means of web-based questionnaires and visits to test centra is planned for every 5th and 10th year, respectively, following the baseline investigation.

The study was approved by The Swedish Data Inspection Board (No. 307-2011).

Purpose:

... Show more..
The study consists of three parts:
1) Collection of data on lifestyle factors by a self-administered web-based questionnaire
2) Visit to a test center for collection of blood samples and recording of physiological parameters
3) The population is followed in registers for occurence of predefined emdpoints.
Repeated collection of data by means of web-based questionnaires and visits to test centra is planned for every 5th and 10th year, respectively, following the baseline investigation.

The study was approved by The Swedish Data Inspection Board (No. 307-2011).

Purpose:

The primary objectives of the EpiHealth study is to provide a resource to study interactions between genotypes and lifestyle factors in a large cohort (aim is 300,000 individuals) derived from the Swedish population in the age range 45-75 years regarding development of common degenerative disorders.

The study is planned to screen 300,000 individuals in Sweden with an age between 45 and 75 years.The data collection is ongoing and takes place via EpiHealth Test Centre in Uppsala and Malmö. In 2011 a pilot study was carried out, including the first 1000 subjects. In April 2015, 20,000 subjects were included. Show less..
Method and outcome

Unit of analysis

Population

Swedish women and men between the ages of 45 and 75 years old.

Sampling procedure

Probability
The sample for the study is based on a random sampling from the population register among individuals between aged 45-75 years. A randomization procedure will assure that all age groups and both genders are equally represented. Inclusion criteria are age 45-75 years, a permanent address in Sweden and a Swedish civic registration number.

Time period(s) investigated

2011 – Ongoing

Biobank is connected to the study

Yes

Number of individuals/objects

20000

Data format / data structure

Data collection

Data collection 1

  • Mode of collection: Web-based interview
  • Time period(s) for data collection: 2011–ongoing
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2011–ongoing
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 3

  • Time period(s) for data collection: 2011–ongoing
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts
Geographic coverage

Geographic spread

Geographic description: Initial two test centers: Malmö and Uppsala

Administrative information

Ethics Review

Uppsala - Ref. 2010/402

Publications

Lind L, Elmståhl S, Bergman E, Englund M, Lindberg E, Michaelsson K, Nilsson PM, Sundström J. EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases. European Journal of Epidemiology, 2013 Feb;28(2):189-97
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