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Sleep and Health in Men (SHM)

SND-ID: ext0173-1.

Is part of collection at SND: Swedish Cohort Consortium (Cohorts.se)

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Creator/Principal investigator(s)

Eva Lindberg - Uppsala University, Department of Medical Sciences

Research principal

Uppsala University - Department of Medical Sciences rorId

Description

Sleep and Health in Men (SHM) started in 1984 when participants were first investigated with postal questionnaires and a subgroup underwent full whole-night polysomnography. At that time this was the first population-based study world-wide on the prevalence of obstructive sleep apnea syndrome. Since then the cohort has been investigated another two times U1994 and 2007) with postal questionnaires and subgroups have been studied with whole-night sleep registrations, blood sampling, anthromometric measurements and oral glucose tolerance tests (OGTT). Information has also been obtained from national registers on mortality, diseases and on occupational accidents.
Apart from being the first population-based prevalence study within the field, data from this cohort have shown that sleep-disordered breathing is a risk factor for cardiovascular morbidity and mortality but also that the risk is age-dependent with higher risks at lower ages while there seem to be no increased risk after about age 60. Furthermore, published data have shown that obstructive sleep apnea syndrome is a progressive disease an

... Show more..
Sleep and Health in Men (SHM) started in 1984 when participants were first investigated with postal questionnaires and a subgroup underwent full whole-night polysomnography. At that time this was the first population-based study world-wide on the prevalence of obstructive sleep apnea syndrome. Since then the cohort has been investigated another two times U1994 and 2007) with postal questionnaires and subgroups have been studied with whole-night sleep registrations, blood sampling, anthromometric measurements and oral glucose tolerance tests (OGTT). Information has also been obtained from national registers on mortality, diseases and on occupational accidents.
Apart from being the first population-based prevalence study within the field, data from this cohort have shown that sleep-disordered breathing is a risk factor for cardiovascular morbidity and mortality but also that the risk is age-dependent with higher risks at lower ages while there seem to be no increased risk after about age 60. Furthermore, published data have shown that obstructive sleep apnea syndrome is a progressive disease and that symptoms of sleep-disordered breathing is an independent risk factor for occupational accidents. This study was also the first community-based cohort study to report an association between breathing disturbances during sleep and impaired insulin sensitivity. These data are still cited and this area constitutes today a large research area world-wide. We recently published data from this cohort showing that weight gain is an independent risk factor for developing sleep disturbances and daytime sleepiness.

Purpose:

The main aim of this population-based cohort study is to analyze risk factors for and long term evolution of sleep disturbances with main focus on sleep-disordered breathing. Another aim is to study consequences of sleep disturbances over time such as accidents and consequences for cardiovascular morbidity and mortality as well as effects on glucose metabolism. Show less..
Method and outcome

Unit of analysis

Time Method

Sampling procedure

Data format / data structure

Data collection

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1984 – 2007
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1996 – 1998
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 3

  • Mode of collection: Laboratory observation
  • Time period(s) for data collection: 2007 – 2007
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts
... Show more..

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1984 – 2007
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1996 – 1998
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 3

  • Mode of collection: Laboratory observation
  • Time period(s) for data collection: 2007 – 2007
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts

Data collection 4

  • Mode of collection: Interview
  • Time period(s) for data collection: 2007 – 2007
  • Source of the data: Registers/Records/Accounts: Medical/Clinical, Population group, Registers/Records/Accounts
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Geographic coverage
Administrative information

Responsible department/unit

Department of Medical Sciences

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Public health, global health, social medicine and epidemiology (Standard för svensk indelning av forskningsämnen 2011)

Health (CESSDA Topic Classification)

Keywords

Accidents, Anthropometry, Glucose tolerance test, Sleep apnea syndromes, Sleep wake disorders, Accidents, occupational, Blood sample, National register, Swedish cohort consortium (scc), Cohorts.se

Publications

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Lindberg E, Carter N, Gislason T, Janson C. Role of snoring and daytime sleepiness in occupational accidents. Am J Respir Crit Care Med. 2001 Dec 1;164(11):2031-5.
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Lindberg E, Theorell-Haglöw J, Svensson M, Gislason T, Berne C, Janson C. Sleep apnea and glucose metabolism - a long-term follow-up in a community-based sample. Chest. 2012 Oct;142(4):935-42.
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