The Swedish Mammography Cohort (SMC) is a large population-based cohort of over 60,000 women in the counties of Uppsala and Västmanland. All women born 1914-1948 who were residing in Västmanland and Uppsala County and in the years 1987-1990 received an invitation to participate in a mammography screening programme. The invitation included a six-page questionnaire that sought information on diet and alcohol intake (67-item food frequency questionnaire), parity, age at first childbirth, family history of breast cancer, weight, height, education level, and marital status. Approximately 66,000 women answered the questionnaire.

In the autumn 1997, a second survey was sent to these women to update the information about their eating habits. Additional follow-ups were done 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., breast, colorectal, endometrium, ovary, and renal cell cancer), myocardial infarction, stroke, osteoporosis, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The general aim of the Swedish Mammography Cohort (SMC) is to assess relationships between a number of modifiable factors (diet, vitamin supplement use, physical activity, smoking, alcohol, body weight, other anthropometric measures etc.) and the occurrence of several major chronic diseases.

The questionnaires used in the Swedish Mammography Cohort are the same as the ones that have been used in the Cohort of Swedish Men (COSM).

For more detailed information please visit the SIMPLER website, https://www.simpler4health.se/w/sh/en/researchers/cohorts.

For restrictions in data use see https://www.simpler4health.se/w/sh/en/researchers/rules-and-guidelines and https://www.simpler4health.se/w/sh/en/researchers/publication-policy. Show less..

Data contains personal data

Yes

Sensitive personal data

Yes

Type of personal data

health data

Code key exists

Yes

Language

English

Swedish

Method and outcome

Population

Women born 1914-1948 living in Västmanland or Uppsala County during 1987-1990.

Study design

Observational study

Cohort study

Description of study design

Longitudinal cohort study

Sampling procedure

Total universe/Complete enumeration

From 1987 to 1990, all women who lived in the Uppsala County of central Sweden and were born between 1914-1948 and all women who lived in the adjacent Västmanland County and were born between 1917-1948 received an invitation by mail to participate in a mammography screening program. Included in the mail was also an invitation to participate in this research study and a questionnaire to be answered and returned. Follow-ups have been performed approximately every tenth year starting in 1997. At next follow-up, 2008/2009, the questionnaire was extended and separated into two questionnaires. An additional follow-up was done during 2019.

Time period(s) investigated

1987 – Ongoing

Biobank is connected to the study

The study has collected samples/material which are stored in a scientific collection or biobank

Scientific collection or biobank name: Uppsala biobank/SIMPLER

Type(s) of sample: DNA

Response rate/participation rate

1987: 74%
1997: 70%
2008: 63%
2009: 84%
2019 health: 55%
2019 lifestyle: 83%

Sub-cohort 1: 65%

Data format / data structure

Numeric

Text

Data collection

Data collection 1

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 1987 – 1990
Sample size: 90303
Number of responses: 61433
Source of the data: Population group

Data collection 2

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 1997 – 1997-09-15
Sample size: 56030
Number of responses: 38984
Source of the data: Population group

Data collection 3

Description of the mode of collection: Clinical Subcohort visit 1 Uppsala
Time period(s) for data collection: 2003 – 2009
Sample: blood, urine, faeces, adipose, DNA
Sample size: 8311
Number of responses: 5022
Source of the data: Population group

Data collection 1

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 1987 – 1990
Sample size: 90303
Number of responses: 61433
Source of the data: Population group

Data collection 2

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 1997 – 1997-09-15
Sample size: 56030
Number of responses: 38984
Source of the data: Population group

Data collection 3

Description of the mode of collection: Clinical Subcohort visit 1 Uppsala
Time period(s) for data collection: 2003 – 2009
Sample: blood, urine, faeces, adipose, DNA
Sample size: 8311
Number of responses: 5022
Source of the data: Population group

Data collection 4

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 2008 – 2008-12-31
Sample size: 48253
Number of responses: 30621
Source of the data: Population group

Data collection 5

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 2009 – 2009-06-30
Sample size: 30134
Number of responses: 25332
Source of the data: Population group

Data collection 6

Description of the mode of collection: Clinical Subcohort visit 1 – Västerås
Time period(s) for data collection: 2010 – 2019
Sample: blood, urine, faeces, adipose, DNA
Number of responses: 2630

Data collection 7

Description of the mode of collection: Clinical Subcohort visit 2 – Uppsala
Time period(s) for data collection: 2015 – 2015
Sample: blood, urine, faeces, adipose, DNA
Number of responses: 1500
Source of the data: Population group

Data collection 8

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 2019-01-21 – 2019-06-30
Sample size: 34473
Number of responses: 19081
Source of the data: Population group

Data collection 9

Mode of collection: Self-administered questionnaire
Time period(s) for data collection: 2019-09-16 – 2019-12-31
Sample size: 18930
Number of responses: 14922
Source of the data: Population group

Show less..

Geographic coverage

Geographic spread

Geographic location: Sweden

Geographic description: Uppsala and Västmanland counties, Sweden.

Lowest geographic unit

Municipality

Highest geographic unit

Country

Administrative information

Responsible department/unit

Department of Surgical Science

Ethics Review

Uppsala - Ref. 2018/262

Uppsala - Ref. 2018/263

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Cancer and oncology (Standard för svensk indelning av forskningsämnen 2011)

Endocrinology and diabetes (Standard för svensk indelning av forskningsämnen 2011)

Cardiac and cardiovascular systems (Standard för svensk indelning av forskningsämnen 2011)

Orthopaedics (Standard för svensk indelning av forskningsämnen 2011)

Geriatrics (Standard för svensk indelning av forskningsämnen 2011)

General practice (Standard för svensk indelning av forskningsämnen 2011)

Public health, global health, social medicine and epidemiology (Standard för svensk indelning av forskningsämnen 2011)

Nutrition and dietetics (Standard för svensk indelning av forskningsämnen 2011)

Keywords

Anthropometry, Cohort studies, Hearing, Life style, Follow-up studies, Heart failure, Longitudinal studies, Prospective studies, Exercise, Population surveillance, Osteoporosis, Survival, Tinnitus, Climacteric, Arthritis, rheumatoid, Drug therapy, Hormone replacement therapy, Risk factors, Women's health, Myocardial infarction, Stroke, Diet, Alcohol drinking, Medical history taking, Work, Asthma, Fractures, bone, Thrombosis, Bronchitis, chronic, Breast cyst, Breast neoplasms, Crohn disease, Diabetes mellitus, Cause of death, Eczema, Obesity, Reproductive history, Leisure activities, Intermittent claudication, Gallstones, Pregnancy, Cataract, Glaucoma, Dermatitis, atopic, Health, Health status, Hypertension, Irritable bowel syndrome, Cholesterol, Dietary supplements, Pulmonary disease, chronic obstructive, Body height, Body weight, Angina pectoris, Arthralgia, Uterine neoplasms, Lung neoplasms, Drug utilization, Gastritis, Mammography, Menstruation, Migraine disorders, Environmental medicine, Multiple sclerosis, Oral health, Depression, Kidney calculi, Kidney neoplasms, Parkinson disease, Contraceptive agents, Psoriasis, Registries, Rhinitis, allergic, seasonal, Smoking, Disease, Social support, Stress, psychological, Vision, ocular, Sleep, Colonic neoplasms, Colitis, ulcerative, Vitamins, Vertigo, Ovarian neoplasms, Heredity, Hypersensitivity, Cohorts.se, Swedish cohort consortium (scc), Near - national e-infrastructure for aging research

Publications

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.
DOI: https://doi.org/10.13172/2053-079X-1-2-943

Link to publication list:

Publications SIMPLER

If you have published anything based on these data, please notify us with a reference to your publication(s). If you are responsible for the catalogue entry, you can update the metadata/data description in DORIS.