The Cohort of Swedish Men (COSM)

SND-ID: ext0015-1.

Is part of collection at SND: SIMPLER - Swedish Infrastructure for Medical Population-Based Life-Course and Environmental Research, Swedish Cohort Consortium (Cohorts.se)

Citation

Creator/Principal investigator(s)

Karl Michaëlsson - Uppsala University, Department of Surgical Sciences orcid

Research principal

Uppsala University - Department of Surgical Science rorId

Description

The Cohort of Swedish Men is a large population-based cohort of over 45,000 men in the counties of Västmanland and Örebro. All men born 1918-1952 who were residing in Västmanland and Örebro County in 1997 received an invitation to participate in this research study and a questionnaire to answer and return. The questionnaire included information about modifiable lifestyle factors such as diet, physical activity, smoking, weight, use of dietary supplements, some prescribed drugs, alcohol intake in addition to some gender specific questions.

Approximately 48,000 men responded. Follow-ups were done during 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., prostate, colorectal and renal cell cancer), myocardial infarction, stroke, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The questionnaires used in the

... Show more..
The Cohort of Swedish Men is a large population-based cohort of over 45,000 men in the counties of Västmanland and Örebro. All men born 1918-1952 who were residing in Västmanland and Örebro County in 1997 received an invitation to participate in this research study and a questionnaire to answer and return. The questionnaire included information about modifiable lifestyle factors such as diet, physical activity, smoking, weight, use of dietary supplements, some prescribed drugs, alcohol intake in addition to some gender specific questions.

Approximately 48,000 men responded. Follow-ups were done during 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., prostate, colorectal and renal cell cancer), myocardial infarction, stroke, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The questionnaires used in the Cohort of Swedish men are the same as the ones that have been used in the Swedish Mammography Cohort (SMC).

A clinical examination of a subcohort of COSM living in Västerås was conducted between 2010 and 2019. Participants with urological cancer have been sampled at the urological clinic at the hospital in Örebro
since 2014. In 2014, researchers at Örebro University and Örebro Hospital started collecting blood samples (whole blood, plasma, and serum) from members of COSM with incident urological cancer (prostate, kidney, bladder, and penile cancer). Urine is additionally collected from prostate cancer patients. To date, samples from 232 prostate cancer cases have been collected.



For more detailed information please visit the SIMPLER website, https://www.simpler4health.se/w/sh/en/researchers/cohorts.

For restrictions in data use see https://www.simpler4health.se/w/sh/en/researchers/rules-and-guidelines and https://www.simpler4health.se/w/sh/en/researchers/publication-policy. Show less..

Data contains personal data

Yes

Sensitive personal data

Yes

Type of personal data

health data

Code key exists

Yes

Language

Method and outcome

Population

Men born 1918-1952 in Örebro and Västmanland counties.

Study design

Observational study

Cohort study

Description of study design

Longitudinal cohort study

Sampling procedure

Total universe/Complete enumeration
In 1997 all men who lived in Västmanland or Örebro County and were born 1918-1952 received an invitation by mail to participate in this research study together with a questionnaire to be answered and returned. Follow-ups have been performed approximately every tenth year starting in 2008. At the follow-up 2008/2009 the questionnaire was extended and separated into two questionnaires. An additional follow-up was done during 2019.

Time period(s) investigated

1997 – Ongoing

Biobank is connected to the study

The study has collected samples/material which are stored in a scientific collection or biobank

Scientific collection or biobank name: Uppsala biobank/SIMPLER

Type(s) of sample: DNA

Response rate/participation rate

COSM 1997: response rate 48%
COSM 2008 health: response rate 78%
COSM 2009 lifestyle: response rate 90%
COSM 2019 health: response rate 72%
COSM 2019 lifestyle: response rate 86%

Data format / data structure

Data collection

Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1997 – 1998-01-01
  • Sample size: 100303
  • Number of responses: 45906
  • Source of the data: Population group

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2008 – 2008
  • Sample size: 37861
  • Number of responses: 29503
  • Source of the data: Population group

Data collection 3

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2009 – 2009
  • Sample size: 29068
  • Number of responses: 26156
  • Source of the data: Population group
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Data collection 1

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 1997 – 1998-01-01
  • Sample size: 100303
  • Number of responses: 45906
  • Source of the data: Population group

Data collection 2

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2008 – 2008
  • Sample size: 37861
  • Number of responses: 29503
  • Source of the data: Population group

Data collection 3

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2009 – 2009
  • Sample size: 29068
  • Number of responses: 26156
  • Source of the data: Population group

Data collection 4

  • Description of the mode of collection:
    Clinical Subcohort Västerås.
    Validated cognitive phone interview, a self-administeret food frequency questionnaire and a one-day food diary.
    Health examination including measurement of weight, height, waist, hip, and blood pressure, and body composition measurement using a bio-electrical impedance scale. Samples of fasting blood, urine, faeces and adipose tissue were also collected at the health exam.
  • Time period(s) for data collection: 2010 – 2019
  • Number of responses: 4754
  • Source of the data: Population group

Data collection 5

  • Description of the mode of collection: Clinical Subcohort Örebro
  • Time period(s) for data collection: 2014 – 2014
  • Number of responses: 600
  • Source of the data: Population group

Data collection 6

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2019-01-21 – 2019-06-30
  • Sample size: 26392
  • Number of responses: 18901

Data collection 7

  • Mode of collection: Self-administered questionnaire
  • Time period(s) for data collection: 2019-09-16 – 2019-12-31
  • Sample size: 18746
  • Number of responses: 16166
  • Source of the data: Population group
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Geographic coverage

Geographic spread

Geographic location: Sweden

Geographic description: Örebro och Västmanland counties, Sweden.

Lowest geographic unit

Municipality

Highest geographic unit

Country

Administrative information

Responsible department/unit

Department of Surgical Science

Ethics Review

Uppsala - Ref. 2018/262

Uppsala - Ref. 2018/263

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Cancer and oncology (Standard för svensk indelning av forskningsämnen 2011)

Endocrinology and diabetes (Standard för svensk indelning av forskningsämnen 2011)

Cardiac and cardiovascular systems (Standard för svensk indelning av forskningsämnen 2011)

Orthopaedics (Standard för svensk indelning av forskningsämnen 2011)

Geriatrics (Standard för svensk indelning av forskningsämnen 2011)

General practice (Standard för svensk indelning av forskningsämnen 2011)

Public health, global health, social medicine and epidemiology (Standard för svensk indelning av forskningsämnen 2011)

Nutrition and dietetics (Standard för svensk indelning av forskningsämnen 2011)

Publications

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.
DOI: https://doi.org/10.13172/2053-079X-1-2-943

Link to publication list:

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