The Cohort of Swedish Men (COSM)
SND-ID: ext0015-1.
Is part of collection at SND: SIMPLER - Swedish Infrastructure for Medical Population-Based Life-Course and Environmental Research, Swedish Cohort Consortium (Cohorts.se)
Access to data via
Contact
SIMPLER
Citation
Creator/Principal investigator(s)
Karl Michaëlsson - Uppsala University, Department of Surgical Sciences
Research principal
Uppsala University - Department of Surgical Science
Description
The Cohort of Swedish Men is a large population-based cohort of over 45,000 men in the counties of Västmanland and Örebro. All men born 1918-1952 who were residing in Västmanland and Örebro County in 1997 received an invitation to participate in this research study and a questionnaire to answer and return. The questionnaire included information about modifiable lifestyle factors such as diet, physical activity, smoking, weight, use of dietary supplements, some prescribed drugs, alcohol intake in addition to some gender specific questions.
Approximately 48,000 men responded. Follow-ups were done during 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., prostate, colorectal and renal cell cancer), myocardial infarction, stroke, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The questionnaires used in the
Approximately 48,000 men responded. Follow-ups were done during 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., prostate, colorectal and renal cell cancer), myocardial infarction, stroke, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The questionnaires used in the Cohort of Swedish men are the same as the ones that have been used in the Swedish Mammography Cohort (SMC).
A clinical examination of a subcohort of COSM living in Västerås was conducted between 2010 and 2019. Participants with urological cancer have been sampled at the urological clinic at the hospital in Örebro
since 2014. In 2014, researchers at Örebro University and Örebro Hospital started collecting blood samples (whole blood, plasma, and serum) from members of COSM with incident urological cancer (prostate, kidney, bladder, and penile cancer). Urine is additionally collected from prostate cancer patients. To date, samples from 232 prostate cancer cases have been collected.
For more detailed information please visit the SIMPLER website, https://www.simpler4health.se/w/sh/en/researchers/cohorts.
For restrictions in data use see https://www.simpler4health.se/w/sh/en/researchers/rules-and-guidelines and https://www.simpler4health.se/w/sh/en/researchers/publication-policy. Show less..
Data contains personal data
Yes
Sensitive personal data
Yes
Type of personal data
health data
Code key exists
Yes
Population
Men born 1918-1952 in Örebro and Västmanland counties.
Study design
Observational study
Cohort study
Description of study design
Longitudinal cohort study
Sampling procedure
Time period(s) investigated
1997 – Ongoing
Biobank is connected to the study
The study has collected samples/material which are stored in a scientific collection or biobank
Scientific collection or biobank name: Uppsala biobank/SIMPLER
Type(s) of sample: DNA
Response rate/participation rate
COSM 1997: response rate 48%
COSM 2008 health: response rate 78%
COSM 2009 lifestyle: response rate 90%
COSM 2019 health: response rate 72%
COSM 2019 lifestyle: response rate 86%
Geographic spread
Geographic location: Sweden
Geographic description: Örebro och Västmanland counties, Sweden.
Lowest geographic unit
Municipality
Highest geographic unit
Country
Responsible department/unit
Department of Surgical Science
Ethics Review
Uppsala - Ref. 2018/262
Uppsala - Ref. 2018/263
Research area
Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)
Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)
Cancer and oncology (Standard för svensk indelning av forskningsämnen 2011)
Endocrinology and diabetes (Standard för svensk indelning av forskningsämnen 2011)
Cardiac and cardiovascular systems (Standard för svensk indelning av forskningsämnen 2011)
Orthopaedics (Standard för svensk indelning av forskningsämnen 2011)
Geriatrics (Standard för svensk indelning av forskningsämnen 2011)
General practice (Standard för svensk indelning av forskningsämnen 2011)
Public health, global health, social medicine and epidemiology (Standard för svensk indelning av forskningsämnen 2011)
Nutrition and dietetics (Standard för svensk indelning av forskningsämnen 2011)
Keywords
Anthropometry, Cohort studies, Hearing, Life style, Follow-up studies, Heart failure, Longitudinal studies, Prospective studies, Exercise, Population surveillance, Survival, Tinnitus, Urination disorders, Arthritis, rheumatoid, Drug therapy, Risk factors, Myocardial infarction, Stroke, Diet, Alcohol drinking, Medical history taking, Work, Asthma, Fractures, bone, Thrombosis, Bronchitis, chronic, Crohn disease, Diabetes mellitus, Cause of death, Eczema, Obesity, Leisure activities, Intermittent claudication, Gallstones, Cataract, Glaucoma, Dermatitis, atopic, Health, Health status, Hypertension, Irritable bowel syndrome, Cholesterol, Dietary supplements, Pulmonary disease, chronic obstructive, Body height, Body weight, Angina pectoris, Arthralgia, Lung neoplasms, Drug utilization, Gastritis, Migraine disorders, Environment, Multiple sclerosis, Oral health, Depression, Kidney calculi, Kidney neoplasms, Parkinson disease, Prostatic neoplasms, Psoriasis, Registries, Rhinitis, allergic, seasonal, Smoking, Disease, Social support, Stress, psychological, Vision, ocular, Sleep, Colonic neoplasms, Colitis, ulcerative, Vitamins, Vertigo, Heredity, Hypersensitivity, Swedish cohort consortium (scc), Near - national e-infrastructure for aging research, Cohorts.se
Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.
DOI:
https://doi.org/10.13172/2053-079X-1-2-943
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