The primary prevention study 1974-1977
SND-ID: snd0011-2.
Is part of collection at SND: Swedish Cohort Consortium (Cohorts.se)
Access to data via
Contact
Annika Rosengren
Creator/Principal investigator(s)
Annika Rosengren - University of Gothenburg, Department of Emergency and Cardiovascular Medicine
Lars Wilhelmsen - University of Gothenburg, Department of Emergency and Cardiovascular Medicine
Research principal
University of Gothenburg
- Department of Emergency and Cardiovascular Medicine
Description
The Primary Prevention Trial in Goteborg is a multifactorial intervention programme on coronary heart disease, stroke incidence and total mortality. The study is administered by the Section for Preventive Cardiology, Institution of Medicine, University of Gothenburg. The study started in 1970. The intervention group consisted of 10 004 men. Two control groups were of similar size. The participants were all men in Gothenburg born in 1915-1922 and 1924-1925. The first examined group was men born in 1915 and the first screening was completed 1973 with those born in 1925. A second examination started in 1974 and was completed in early spring 1977, and the final examination was performed ten years after the first one, that is between 1980 and 1983. The participants were 47-55 years of age when the study started, and accordingly 57-65 years of age at the final examination. Participation rate at the first screening examination was 75% (n=7495). The intervention group and a 2% sample of the control group 1 received an illustrated postal questionnaire dealing with family history of heart disease and s
... Show more..Data from the intervention group are available from SND.
Purpose:
1 - to analyse the extent to which it was possible to induce changes in risk factors in a randomly selected population sample of middle-aged Swedish men by means of a population-based intervention programme which could be managed by a limited number of physicians and paramedical personnel. 2 - to measure the effect of this intervention programme on the incidence of non-fatal and fatal myocardial infarction, stroke and the total death rate in the intervention group compared with two control groups also randomly selected from the general population. Show less..
Data contains personal data
No
Language
Unit of analysis
Population
Men born 1915-1922 och 1924-1925
Time Method
Study design
Experimental study
Sampling procedure
Time period(s) investigated
1970 – 1983
Variables
129
Number of individuals/objects
7122
Response rate/participation rate
75%
Data format / data structure
Geographic spread
Geographic location: Sweden
Geographic description: The municipality of Gothenburg
Lowest geographic unit
Municipality
Responsible department/unit
Department of Emergency and Cardiovascular Medicine
Research area
Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)
Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)
Cardiac and cardiovascular systems (Standard för svensk indelning av forskningsämnen 2011)
Health (CESSDA Topic Classification)
Keywords
Physical examination, Body composition, Electrocardiography, Heart failure, Longitudinal studies, Exercise, Population surveillance, Socioeconomic factors, Drug therapy, Risk factors, Middle aged, Overweight, Mortality, Myocardial infarction, Stroke, Medical history taking, Blood glucose, Diabetes mellitus, Epidemiology, Obesity, Cardiovascular diseases, Health, Hypertension, Insulin, Coffee, Cholesterol, Coronary disease, Body height, Body weight, Angina pectoris, Smoking, Disease, Morbidity, Delivery of health care, Stress, psychological, Sleep wake disorders, Triglycerides, Heredity, Swedish cohort consortium (scc), Cohorts.se
Jood K, Jern C, Wilhelmsen L, Rosengren A. Body mass index in mid-life is associated with a first stroke in men: a prospective population study over 28 years. Stroke 2004;35:2764-9.
Rosengren A, Skoog I, Gustafson D, Wilhelmsen L. Body mass index, other cardiovascular risk factors, and hospitalization for dementia. Arch Intern Med 2005;165:321-6.
Eriksson P, Wilhelmsen L, Rosengren A. Bundle-branch block in middle-aged men: risk of complications and death over 28 years. The Primary Prevention Study in Goteborg, Sweden. Eur Heart J 2005;26:2300-6.
Schaufelberger M, Rosengren A. Heart failure in different occupational classes in Sweden. Eur Heart J 2007;28:212-8.
Rosengren A, Fredén M, Hansson PO, Wilhelmsen L, Wedel H, Eriksson H. Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men. J Thromb Haemost 2008;6:558-64.
Adlerberth AM, Rosengren A, Wilhelmsen L. Diabetes and long-term risk of mortality from coronary and other causes in middle-aged Swedish men. A general population study. Diabetes Care. 1998 Apr;21(4):539-45.
Almgren T, Persson B, Wilhelmsen L, Rosengren A, Andersson OK. Stroke and coronary heart disease in treated hypertension - a prospective cohort study over three decades. J Intern Med. 2005 Jun;257(6):496-502.
Rosengren A, Tibblin G, Wilhelmsen L. Self-perceived psychological stress and incidence of coronary artery disease in middle-aged men. Am J Cardiol 1991;68:1171-5.
Wilhelmsen L, Berglund G, Elmfeldt D, et al. The multifactor primary prevention trial in Göteborg, Sweden. Eur Heart J 1986;7:279-88.
Molnár P, Stockfelt L, Barregard L, Sallsten G. Residential NOx exposure in a 35-year cohort study. Changes of exposure, and comparison with back extrapolation for historical exposure assessment. Atmospheric Environment 115 (2015) 62e69. doi:10.1016/j.atmosenv.2015.05.055.
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Stockfelt L, Andersson EM, Molnár P, Rosengren A, Wilhelmsen L, Sallsten G, Barregard L. Long term effects of residential NOx exposure on total and cause-specific mortality and incidence of myocardial infarction in a Swedish cohort. EnvironmentalResearch142(2015)197-206. doi:10.1016/j.envres.2015.06.045
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