Umbilical cord blood was taken from 48000 new born children in the county of Skåne in order to determine the risk of hereditary type 1 diabetes. Of the screened children 7,4% had an increased risk. Of these, 2,525 children participate in the study follow-up part. TEDDY children will be followed until they are 15 years old. Up until 4 years of age, the child visits a TEDDY office every 3 months. After 4 years of age, the visits takes place two times per year. If the child shows signs of an autoimmune process started, that the child has acquired antibodies in the blood, the child are followed-up every three months in the future. The study includes blood, feaces, urine and saliva samples as well as samples from the nails. Height and weight are recorded and children's physical activity is measured. Food Diary conducted during periods and sample on the family's tap water is taken. Further interviews are conducted and the parents respond to different questionnaires.

Purpose:
To identify environmental exposures that are associated with increased risk of developing autoantibodies against pancreatic

Data contains personal data

Yes

Sensitive personal data

Yes

Type of personal data

Medical data

Code key exists

Yes

Method and outcome

Unit of analysis

Individual

Time period(s) investigated

2004-09 – Ongoing

Data format / data structure

Numeric

Data collection

Data collection 1

Mode of collection: Physical measurements and tests
Time period(s) for data collection: 2004-09 – 2010-02
Sample size: 48000
Source of the data: Population group, Biological samples

Data collection 2

Mode of collection: Face-to-face interview
Sample size: 2525
Source of the data: Population group

Geographic coverage

Geographic spread

Geographic description: Scania (5 additional centres in USA,Finland and Germany)

Administrative information

Responsible department/unit

Department of Clinical Sciences

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Endocrinology and diabetes (Standard för svensk indelning av forskningsämnen 2011)

Health (CESSDA Topic Classification)

Keywords

Children, Insulin, Diabetes mellitus, type 1, Ambient exposure, Scania, Epihealth, Gad65, Ia-2, Znt8, Viral infections, Epihealth_skåne

Publications

Link to publication list:

Publikationer

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