mRNA sequencing and LC-MS data for: Exposure of colon-derived epithelial monolayers to fecal luminal factors from patients with colon cancer and ulcerative colitis results in distinct gene expression patterns
SND-ID: 2024-455. Version: 1. DOI: https://doi.org/10.5878/bdc2-kk22
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Associated documentation
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Citation
Creator/Principal investigator(s)
Maria Magnusson
- University of Gothenburg, Institute of Biomedicine
Research principal
Description
The dataset contains:
Two document files where method and collection of data is explained.
One tabular data file containing results from the analysis.
Data contains personal data
No
Language
Population
Patients with ulcerative colitis, patients with colon cancer and healthy individuals.
Time Method
Study design
Experimental study
Description of study design
See attached file "Data collection and method"
Time period(s) investigated
2018 – 2019
Biobank is connected to the study
This study has used existing samples from a scientific collection or biobank
Data format / data structure
Funding 1
-
Funding agency:
Swedish Research Council
- Funding agency's reference number: 2019-01052, 2018-02566
Funding 2
- Funding agency: Apotekare Hedbergs foundation
- Project name on the application: Resolution av inflammation hos patienter med ulcerös kolit
Funding 3
-
Funding agency:
ALF-agreement
- Funding agency's reference number: ALFGBG-723921, ALFGBG-722331, ALFGBG-965619
Ethics Review
Gothenburg - Ref. Dnr 563-02
Gothenburg - Ref. Dnr 233-10
Gothenburg - Ref. Dnr 988-14
Research area
Cell biology (Standard för svensk indelning av forskningsämnen 2011)
Immunology (Standard för svensk indelning av forskningsämnen 2011)
Gastroenterology and hepatology (Standard för svensk indelning av forskningsämnen 2011)
Moraes Holst, L., Iribarren, C., Sapnara, M., Savolainen, O., Törnblom, H., Wettergren, Y., Strid, H., Simrén, M., Magnusson, M. K., & Öhman, L. (n.d.). Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and Colonoids. In International Journal of Molecular Sciences (No. 15505; Vol. 23, Issue 24). https://doi.org/10.3390/ijms232415505
DOI:
https://doi.org/10.3390/ijms232415505
SwePub:
oai:gup.ub.gu.se/323826
Iribarren, C., Nordlander, S., Sundin, J., Isaksson, S., Savolainen, O., Törnblom, H., Magnusson, M. K., Simrén, M., & Öhman, L. (n.d.). Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids. In Neurogastroenterology and Motility (Vol. 34, Issue 10). https://doi.org/10.1111/nmo.14390
DOI:
https://doi.org/10.1111/nmo.14390
SwePub:
oai:gup.ub.gu.se/316392
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