Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1
SND-ID: 2021-195-1.
Is part of collection at SND: NEAR - National E-Infrastructure for Aging Research in Sweden
Access to data via
Contact
Linda Hassing
Creator/Principal investigator(s)
Linda Hassing
- University of Gothenburg, Department of Psychology
Research principal
University of Gothenburg
- Department of Psychology
Description
The OCTO-Twin Study aims to investigate the etiology of individual differences among twin-pairs age 80 and older, on a range of domains including health and functional capacity, cognitive functioning, psychological well-being, personality and personal control. In the study, twin pairs were withdrawn from the Swedish Twin Registry. At the first wave, the twins had to be born 1913 or earlier and both partners in the pair had to accept participation. At baseline in 1991-94, 351 twin pairs (149 monozygotic and 202 like-sex dizygotic pairs) were investigated (mean age: 83.6 years and 67% were female). The two-year longitudinal follow-ups were conducted on all twins who were alive and agreed to participate. Data have been collected at five waves over a total of eight years.
The in-person testing included interviews, a health examination including blood pressure and lung function, blood sampling, and tests on functional capacity, cognitive abilities, and memory.
• The participants were examined as follows: physical and mental health status; selected personality dimensions; activities of daily livi
The in-person testing included interviews, a health examination including blood pressure and lung function, blood sampling, and tests on functional capacity, cognitive abilities, and memory.
• The participants were examined as follows: physical and mental health status; selected personality dimensions; activities of daily living; health-related behaviors of smoking, alcohol consumption and legal drug use; early rearing environment, and the adult working, family and social environments.
• Physical measures included: blood pressure, pulse, anthropometric measures, lung function, grip strength, physical performances measures for upper and lower body functional activity, and assessment of activities of daily living measures (e.g. turn key in lock, pour a glass of water). Fasting blood and morning urine samples were also collected.
• The cognitive battery was designed to represent the domains of crystallized and fluid intelligence and memory. The battery included the Mini-Mental Status Examinations (MMSE); Information test, Synonyms test, Analogies test, Figure logic test, Block design test, Digit span (Forward and Backward) test, Picture memory test, Symbol Digit test. Dementia diagnoses have been assigned following assessment of cognitive performance and review of medical records giving a consensus diagnosis.
Refer to the individual datasets in the NEAR portal for more details on variable groups and individual variables. Show less..
Data contains personal data
Yes
Sensitive personal data
Yes
Type of personal data
Pseudonymised data related to mental and physical health, as well as socio-demographics and social relationships
Code key exists
Yes
Unit of analysis
Population
Twin pairs from the Swedish Twin Registry who were born 1913 or earlier and were at the age of 80 years at baseline.
Study design
Observational study
Cohort study
Cohort study: Prospective
Description of study design
Longitudinal study
Time period(s) investigated
1991 – 1994
Variables
1062
Number of individuals/objects
702
Data format / data structure
Geographic spread
Geographic location: Sweden
Responsible department/unit
Department of Psychology
Identifiers
Ethics Review
Other - Ref. S-005011-50
Approval of Assurance to Comply with 45 CFR 46. Public Health Service, National Institutes of Health, USA. Office for Protection from Research Risks. July 20, 1999. Accepted by the ethical committee of the Karolinska Institute
Research area
Gerontology, specialising in medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)
Psychology (Standard för svensk indelning av forskningsämnen 2011)
Keywords
Activities of daily living, Aged, 80 and over, Epidemiologic studies, Dementia, Life style, Geriatrics, Memory, Longitudinal studies, Neuropsychological tests, Socioeconomic factors, Body mass index, Genes, Cognition, Environment, Depression, Personality, Mental health, Registries, Diabetes mellitus, type 2, Heredity, Quality of life, Twin study, Aging, Apolipoproteins e, Memory disorders, Nerve degeneration, Wechsler scales, Degenerative disease of nervous system unspecified, Mental status and dementia tests, Wechsler memory scale, Apoe genotype, Functional status, Memory function, Social interaction, Near - national e-infrastructure for aging research, Functional ability, Social life
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DOI:
https://doi.org/10.1024/1662-9647/a000138
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Handle:
https://hdl.handle.net/2077/17873
ISBN:
9789162876012
Wikby, A., Ferguson, G. F., Forsey, R., Thompson, J., Strindhall, J., Löfgren, S., Nilsson, B.-O., Ernerudh, J., Pawelec, G., & Johansson, B. (2005). An immune risk phenotype, cognitive impairment and survival in very late life: The impact of alostatic load in Swedish Octo- and Nongenarian humans. In The Journals of Gerontology: Series A, Volume 60, Issue 5 (pp. 556–565).
DOI:
https://doi.org/10.1093/gerona/60.5.556
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DOI:
https://doi.org/10.1126/science.276.5318.1560
Hassing, L. (2020). Gender Differences in the Association Between Leisure Activity in Adulthood and Cognitive Function in Old Age: A Prospective Longitudinal Population-Based Study. In The journals of gerontology. Series B, Psychological sciences and social sciences (Vol. 75, Issue 1, pp. 11-20).
DOI:
https://doi.org/10.1093/geronb/gbx170
SwePub:
oai:gup.ub.gu.se/266566
Johansson, B., Johansson, B., McClearn, G., & Pedersen, N. (2003). Health, biobehavioral functioning, and personality in the oldest-old: The Swedish OCTO-Twin Study. Presented at the 56th Annual Scientific Meeting of the Gerontological Society of America, San Diego. In GERONTOLOGIST (Vol. 43, Special Issue 1, p. 507).
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DOI:
https://doi.org/10.1093/geronb/gbw006
SwePub:
oai:gup.ub.gu.se/243248
Hofer, S. M., Johansson, B., Berg, S., Pedersen, N. L., & McClearn, G. E. (2001). Changes in Cognitive Functioning in the Oldest-Old Twins : The Octo-Twin Study. Presented at the 54th Annual Scientific Meeting of the Gerontological Society of America, Chicago. In GERONTOLOGIST (Vol. 41, Special Issue 1, p. ?).
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DOI:
https://doi.org/10.1016/S0047-6374(03)00024-1
URN:
urn:nbn:se:liu:diva-26438
SwePub:
oai:DiVA.org:liu-26438
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