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Association of Gut Microbial Clostridia With Brain Functional Connectivity and Gastrointestinal Sensorimotor Function in Patients With Irritable Bowel Syndrome, Based on Tripartite Network Analysis

SND-ID: snd1082-1. Version: 1.0. DOI: https://doi.org/10.5878/ejpj-p674

Citation

Creator/Principal investigator(s)

Magnus Simrén - University of Gothenburg

Research principal

University of Gothenburg - Department of internal medicine and clinical nutrition rorId

Description

Clinical study assessing the interactions among the brain, gut, and microbiota affect the pathophysiology of irritable bowel syndrome (IBS). Data comes from a larger study where the role of gut microbiota for symptoms in IBS is explored, including interactions with other pathophysiological factors. (Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. (2019) )

Language

Method and outcome

Unit of analysis

Population

IBS and healthy controls; gut microbiota-brain-symptom interactions

Time Method

Sampling procedure

Other
Clinical sample of IBS patients; healthy volunteers

Time period(s) investigated

2010 – 2015

Data format / data structure

Data collection
Geographic coverage

Geographic spread

Geographic location: Sweden

Administrative information

Responsible department/unit

Department of internal medicine and clinical nutrition

Ethics Review

Gothenburg - Ref. 731-09

Topic and keywords

Research area

Medical and health sciences (Standard för svensk indelning av forskningsämnen 2011)

Clinical medicine (Standard för svensk indelning av forskningsämnen 2011)

Gastroenterology and hepatology (Standard för svensk indelning av forskningsämnen 2011)

Health (INSPIRE topic categories)

Health (CESSDA Topic Classification)

Keywords

Irritable bowel syndrome, Gut microbiota

Publications

Labus, J.S., Osadchiy, V., Hsiao, E.Y. et al. Evidence for an association of gut microbial Clostridia with brain functional connectivity and gastrointestinal sensorimotor function in patients with irritable bowel syndrome, based on tripartite network analysis. Microbiome 7, 45 (2019) doi:10.1186/s40168-019-0656-z
Link to article
DOI: https://doi.org/10.1186/s40168-019-0656-z

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Versions

Version 1.0. 2019-02-05

Version 1.0: 2019-02-05

DOI: https://doi.org/10.5878/ejpj-p674

Published: 2019-02-05
Last updated: 2019-12-10