Malmö Preventive Project

SND-ID: ext0013-1.

Is part of collection at SND: Scania Metadatabase for Epidemiology (SME)

Creator/Principal investigator(s)

Jonas Manjer - Lund University, Faculty of Medicine

Olle Melander - Lund University, Faculty of Medicine

Peter M Nilsson - Lund University, Faculty of Medicine

Research principal

Lund University - Faculty of Medicine rorId

Description

The MPP was started in the early 70's as a screening survey in the middle-aged population of Malmö, the third largest city of Sweden. Subjects born in Malmö and residents of the city were invited for a clinical examination, questionnaire and blood sampling. In all 22,444 men and 10,902 women participated during the period 1974-1992. During a later follow-up, the MPP-Re-examination (MPP-RES) in all 17,284 of the original screenes attended in 2002-2006.

Purpose:
1. To screen for cardiovascular risk-factors and alcohol abuse in the local population, and to offer intervention to subjects at risk;

2. To use DNA (at MPP-RES) for analyses of genetic risks of type-2 diabetes and cardiovascular disease, as well as some cancers.

Data contains personal data

Yes

Sensitive personal data

Yes

Method and outcome

Unit of analysis

Population

Individuals at age 35-70 y at first screening living in Malmö

Time period(s) investigated

1974 – 2006

Response rate/participation rate

Baslinjeundersökningen: 33 346 individer, 70% svarsfrekvens
Återundersökning: 17 284 individer, 67% svarsfrekvens

Data format / data structure

Data collection

Data collection 1

  • Mode of collection: Self-administered questionnaire: paper
  • Time period(s) for data collection: 1974 – 1991
  • Source of the data: Population group

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1974 – 1991
  • Source of the data: Population group

Data collection 3

  • Mode of collection: Self-administered questionnaire: paper
  • Time period(s) for data collection: 2002 – 2006
  • Source of the data: Population group
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Data collection 1

  • Mode of collection: Self-administered questionnaire: paper
  • Time period(s) for data collection: 1974 – 1991
  • Source of the data: Population group

Data collection 2

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 1974 – 1991
  • Source of the data: Population group

Data collection 3

  • Mode of collection: Self-administered questionnaire: paper
  • Time period(s) for data collection: 2002 – 2006
  • Source of the data: Population group

Data collection 4

  • Time period(s) for data collection: 2002 – 2006
  • Source of the data: Population group

Data collection 5

  • Mode of collection: Physical measurements and tests
  • Time period(s) for data collection: 2002 – 2006
  • Source of the data: Population group
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Geographic coverage

Geographic spread

Geographic location: Sweden

Geographic description: Municipality of Malmö

Administrative information

Responsible department/unit

Faculty of Medicine

Publications

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Nilsson PM, Nilsson JA, Berglund G. Population-attributable risk of coronary heart disease risk factors during long-term follow-up: the Malmö Preventive Project. J Intern Med 2006;260:134-41.

Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, Tuomi T, Berglund G, Altshuler D, Nilsson P, Groop L. Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 2008;359:2220-32.

Berglund G, Nilsson P, Eriksson KF, Nilsson JA, Hedblad B, Kristenson H, Lindgärde F. Long-term outcome of the Malmö preventive project: mortality and cardiovascular morbidity. J Intern Med. 2000 Jan;247(1):19-29
DOI: https://doi.org/10.1046/j.1365-2796.2000.00568.x

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